EIF5AL1 Antibody

CAT: 0223-56-158Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-158Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
EIF5AL1is a mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity) .
NCBI Gene ID
143244
Swiss Prot
Q6IS14
Accession Number
Q6IS14
Host
Rabbit
Reactivity
Human
Immunogen
This EIF5AL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 amino acids from the C-terminal region of human EIF5AL1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
17 kDa
Fragment
Rabbit Ig
Symbol
EIF5AL1
NCBI Official Name
Eukaryotic translation initiation factor 5A-1-like
NCBI Organism
Homo sapiens
Background Reference 01
Kim, S.C., et al. Mol. Cell 23 (4) :607-618 (2006)
Background Reference 02
Clement, P.M., et al. FEBS J. 273 (6) :1102-1114 (2006)
Background Reference 03
Facchiano, A.M., et al. Protein Eng. 14 (11) :881-890 (2001)
Background Reference 04
Lipowsky, G., et al. EMBO J. 19 (16) :4362-4371 (2000)
Other Product Names
Eukaryotic translation initiation factor 5A-1-like, eIF-5A-1-like, eIF-5A1-like, Eukaryotic initiation factor 5A isoform 1-like, EIF5AL1
Tested Applications
WB, IHC-P, IF
Protein ID
190359775
Physical Properties
Liquid

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