FRAT2 Antibody

• Background:

  The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the WNT signaling pathway. It may be upregulated in tumor progression.

• NCBI Gene ID:

  23401

• Swiss Prot:

  O75474

• Accession Number:

  O75474

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This FRAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-230 amino acids from the C-terminal region of human FRAT2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  24 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  FRAT2

• NCBI Official Name:

  GSK-3-binding protein FRAT2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lee, D.Y., et al. Menopause 17 (5) :1064-1070 (2010)

• Background Reference 02:

  Liu, G.P., et al. Neurobiol. Aging 29 (9) :1348-1358 (2008)

• Background Reference 03:

  Stoothoff, W.H., et al. J. Biol. Chem. 280 (1) :270-276 (2005)

• Background Reference 04:

  Deloukas, P., et al. Nature 429 (6990) :375-381 (2004)

• Other Product Names:

  GSK-3-binding protein FRAT2, Frequently rearranged in advanced T-cell lymphomas 2, FRAT-2, FRAT2

• Tested Applications:

  WB, IHC-P, IF

• Physical Properties:

  Liquid