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PAP Antibody

CAT: 0223-55-991Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-991Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Polymerase that creates the 3'-poly (A) tail of mRNA's. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus.
NCBI Gene ID
10914
Swiss Prot
P51003
Accession Number
P51003
Host
Rabbit
Reactivity
Human
Immunogen
This PAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-435 amino acids from the Central region of human PAP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
83 kDa
Fragment
Rabbit Ig
Symbol
PAPOLA
NCBI Official Name
Poly (A) polymerase alpha
NCBI Organism
Homo sapiens
Background Reference 01
Rapti, A., et al. Mol. Cell. Biochem. 340 (1-2), 91-96 (2010) :
Background Reference 02
Nan, H., et al. J. Invest. Dermatol. 129 (9) :2250-2257 (2009)
Background Reference 03
Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)
Background Reference 04
Dettwiler, S., et al. J. Biol. Chem. 279 (34) :35788-35797 (2004)
Other Product Names
Poly (A) polymerase alpha, PAP-alpha, Polynucleotide adenylyltransferase alpha, PAPOLA, PAP
Tested Applications
WB, IHC-P
Protein ID
59803092
Physical Properties
Liquid

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