SFRP4 Antibody

• Background:

  Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression.

• NCBI Gene ID:

  6424

• Swiss Prot:

  Q6FHJ7

• Accession Number:

  Q6FHJ7

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SFRP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-346 amino acids from the C-terminal region of human SFRP4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  40 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SFRP4

• NCBI Official Name:

  Secreted frizzled-related protein 4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lee, D.Y., et al. Menopause 17 (5) :1064-1070 (2010)

• Background Reference 02:

  Kohno, H., et al. Oncol. Rep. 24 (2) :423-431 (2010)

• Background Reference 03:

  Frank, B., et al. Carcinogenesis 31 (8) :1381-1386 (2010)

• Background Reference 04:

  Huang, D., et al. J. Cancer Res. Clin. Oncol. 136 (3) :395-401 (2010)

• Other Product Names:

  Secreted frizzled-related protein 4, sFRP-4, Frizzled protein, human endometrium, FrpHE, SFRP4, FRPHE

• Tested Applications:

  WB, Flow

• Protein ID:

  61216780

• Physical Properties:

  Liquid