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SFRP1 Antibody

CAT: 0223-63-754Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-754Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SFRP1 encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer.
NCBI Gene ID
6422
Swiss Prot
Q8N474
Accession Number
Q8N474
Host
Rabbit
Reactivity
Human
Immunogen
This SFRP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human SFRP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Cell Cycle, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
35 kDa
Fragment
Rabbit Ig
Symbol
SFRP1
NCBI Official Name
Secreted frizzled-related protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Huang, D., et.al., J. Cancer Res. Clin. Oncol. 136 (3), 395-401 (2010)
Background Reference 02
Yang, Z.Q., et.al., Int. J. Cancer 125 (7), 1613-1621 (2009) .
Other Product Names
Secreted frizzled-related protein 1, FRP-1, sFRP-1, Secreted apoptosis-related protein 2, SARP-2, SFRP1, FRP, FRP1, SARP2
Tested Applications
WB, IHC-P, Flow
Protein ID
61216811
Physical Properties
Liquid

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