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SFRP2 Antibody

CAT: 0223-56-366Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-366Size:400 µL
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Background
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq].
NCBI Gene ID
6423
Swiss Prot
Q96HF1
Accession Number
Q96HF1
Host
Rabbit
Reactivity
Human
Immunogen
This SFRP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human SFRP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
33 kDa
Fragment
Rabbit Ig
Symbol
SFRP2
NCBI Official Name
Secreted frizzled-related protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Von Marschall, Z., et al. Biochem. Biophys. Res. Commun. 400 (3) :299-304 (2010)
Background Reference 02
Pehlivan, S., et al. Cancer Genet. Cytogenet. 201 (2) :128-132 (2010)
Background Reference 03
Kohno, H., et al. Oncol. Rep. 24 (2) :423-431 (2010)
Background Reference 04
Yamamura, S., et al. Mol. Cancer Ther. 9 (6) :1680-1687 (2010)
Other Product Names
Secreted frizzled-related protein 2, FRP-2, sFRP-2, Secreted apoptosis-related protein 1, SARP-1, SFRP2, FRP2, SARP1
Tested Applications
WB, IHC-P
Protein ID
61216828
Physical Properties
Liquid

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