SFRP2 Antibody

• Background :

  This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq].

• NCBI Gene ID :

  6423

• Swiss Prot :

  Q96HF1

• Accession Number :

  Q96HF1

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This SFRP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human SFRP2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  33 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  SFRP2

• NCBI Official Name :

  Secreted frizzled-related protein 2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Von Marschall, Z., et al. Biochem. Biophys. Res. Commun. 400 (3) :299-304 (2010)

• Background Reference 02 :

  Pehlivan, S., et al. Cancer Genet. Cytogenet. 201 (2) :128-132 (2010)

• Background Reference 03 :

  Kohno, H., et al. Oncol. Rep. 24 (2) :423-431 (2010)

• Background Reference 04 :

  Yamamura, S., et al. Mol. Cancer Ther. 9 (6) :1680-1687 (2010)

• Other Product Names :

  Secreted frizzled-related protein 2, FRP-2, sFRP-2, Secreted apoptosis-related protein 1, SARP-1, SFRP2, FRP2, SARP1

• Tested Applications :

  WB, IHC-P

• Protein ID :

  61216828

• Physical Properties :

  Liquid