MIA40 Antibody

• Background:

  CHCHD4, a component of human mitochondria, belongs to a protein family whose members share 6 highly conserved cysteine residues constituting a -CXC-CX (9) C-CX (9) C- motif in the C terminus (Hofmann et al., 2005 [PubMed 16185709]) .

• NCBI Gene ID:

  131474

• Swiss Prot:

  Q8N4Q1

• Accession Number:

  Q8N4Q1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MIA40 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-129 amino acids from the C-terminal region of human MIA40.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Obesity

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  16 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CHCHD4

• NCBI Official Name:

  Mitochondrial intermembrane space import and assembly protein 40

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Daithankar, V.N., et al. Biochemistry 48 (22) :4828-4837 (2009)

• Background Reference 02:

  Chacinska, A., et al. J. Biol. Chem. 283 (44) :29723-29729 (2008)

• Background Reference 03:

  Terziyska, N., et al. FEBS Lett. 581 (6) :1098-1102 (2007)

• Background Reference 04:

  Hofmann, S., et al. J. Mol. Biol. 353 (3) :517-528 (2005)

• Other Product Names:

  Mitochondrial intermembrane space import and assembly protein 40, Coiled-coil-helix-coiled-coil-helix domain-containing protein 4, CHCHD4, MIA40

• Tested Applications:

  WB, IHC-P

• Protein ID:

  62510498

• Physical Properties:

  Liquid