COPE Antibody

• Background :

  The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.

• NCBI Gene ID :

  11316

• Swiss Prot :

  O14579

• Accession Number :

  O14579

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This COPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-300 amino acids from the C-terminal region of human COPE.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Chicken, Hamster, Mouse

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  34 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  COPE

• NCBI Official Name :

  Coatomer subunit epsilon

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

• Background Reference 02 :

  Morikawa, R.K., et al. J. Biol. Chem. 284 (39) :26620-26630 (2009)

• Background Reference 03 :

  Maruyama, S., et al. Mol. Cell. Biochem. 307 (1-2), 73-82 (2008) :

• Background Reference 04 :

  Goryachev, A.B., et al. PLoS Comput. Biol. (12), E172 (2006) :

• Other Product Names :

  Coatomer subunit epsilon, Epsilon-coat protein, Epsilon-COP, COPE

• Tested Applications :

  WB, IHC-P, IF

• Physical Properties :

  Liquid