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COPG Antibody

CAT: 0223-60-774Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-774Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity) .
NCBI Gene ID
22820
Swiss Prot
Q9Y678
Accession Number
Q9Y678
Host
Rabbit
Reactivity
Human
Immunogen
This COPG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 721-750 amino acids from the C-terminal region of human COPG.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
98 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
COPG1
NCBI Official Name
Coatomer subunit gamma-1
NCBI Organism
Homo sapiens
Background Reference 01
Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Background Reference 02
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Background Reference 03
Lippincott-Schwartz, J., et al. Trends Cell Biol. 16 (10), E1-E4 (2006) :
Background Reference 04
Watson, P.J., et al. Traffic 5 (2) :79-88 (2004)
Other Product Names
Coatomer subunit gamma-1, Gamma-1-coat protein, Gamma-1-COP, COPG1, COPG
Tested Applications
WB
Protein ID
12229771
Physical Properties
Liquid

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