CPA6 Antibody

• Background:

  The protein encoded by this gene belongs to the family of carboxypeptidases, which catalyze the release of C-terminal amino acid, and have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Polymorphic variants and a reciprocal translocation t (6;8) (q26; q13) involving this gene, have been associated with Duane retraction syndrome.

• NCBI Gene ID:

  57094

• Swiss Prot:

  Q8N4T0

• Accession Number:

  Q8N4T0

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CPA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-315 amino acids from the Central region of human CPA6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  51 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CPA6

• NCBI Official Name:

  Carboxypeptidase A6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bailey, S.D., et al. Diabetes Care (2010) In press :

• Background Reference 02:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 03:

  Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

• Background Reference 04:

  Sharif, S.A., et al. Arthritis Rheum. 60 (10) :2902-2912 (2009)

• Other Product Names:

  Carboxypeptidase A6, 3417-, CPA6, CPAH

• Tested Applications:

  WB

• Protein ID:

  85683250

• Physical Properties:

  Liquid