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GGCX Antibody

CAT: 0223-55-643Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-643Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes an enzyme which catalyzes the posttranslational modification of vitamin K-dependent protein. Many of these vitamin K-dependent proteins are involved in coagulation so the function of the encoded enzyme is essential for hemostasis. Mutations in this gene are associated with vitamin K-dependent coagulation defect and PXE-like disorder with multiple coagulation factor deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
2677
Swiss Prot
P38435
Accession Number
P38435
Host
Rabbit
Reactivity
Human
Immunogen
This GGCX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 548-578 amino acids from the Central region of human GGCX.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
88 kDa
Fragment
Rabbit Ig
Symbol
GGCX
NCBI Official Name
Vitamin K-dependent gamma-carboxylase
NCBI Organism
Homo sapiens
Background Reference 01
Higgins-Gruber, S.L., et al. J. Biol. Chem. 285 (41) :31502-31508 (2010)
Background Reference 02
King, C.R., et al. Thromb. Haemost. 104 (4) :750-754 (2010)
Background Reference 03
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 04
Ikejiri, M., et al. Int. J. Hematol. 92 (2) :302-305 (2010)
Other Product Names
Vitamin K-dependent gamma-carboxylase, Gamma-glutamyl carboxylase, Peptidyl-glutamate 4-carboxylase, Vitamin K gamma glutamyl carboxylase, GGCX, GC
Tested Applications
WB, IHC-P
Protein ID
84028279
Physical Properties
Liquid

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