ADAM17 Antibody

• NCBI Gene ID:

  6868

• Swiss Prot:

  P78536

• Accession Number:

  NP_003174.3

• Host:

  Goat

• Reactivity:

  Human

• Immunogen:

  The immunogen for this antibody is: LQRQNRVDSKETEC

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Homeostasis

• Purification:

  Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

• Positive Control:

  Cat. No. 1201 - HeLa Cell Lysate

• Concentration:

  500 ug/mL

• Homology:

  Expected Species Reactivity based on sequence homology: Mouse, Rat

• Buffer:

  Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and store at -20˚ C. Minimize freezing and thawing.

• Specificity:

  This antibody is expected to recognise isoform 1 (represented by NP_003174.3) and not isoform 2 (represented by NP_068604) .

• Applications Notes:

  Peptide ELISA: Western Blot:Immunohistochemistry:

• Symbol:

  ADAM17

• NCBI Official Name:

  ADAM metallopeptidase domain 17

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Black RA, Rauch CT, Kozlosky CJ, Peschon JJ, Slack JL, Wolfson MF, Castner BJ, Stocking KL, Reddy P, Srinivasan S, Nelson N, Boiani N, Schooley KA, Gerhart M, Davis R, Fitzner JN, Johnson RS, Paxton RJ, March CJ, Cerretti DP A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. Nature. 1997 Feb 20;385 (6618) :729-33

• Other Product Names:

  ADAM17, TACE, a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme), CSVP, cSVP, CD156b, CD156b, MGC71942, TACE, cSVPADAM metallopeptidase domain 17, TNF-alpha converting enzyme, a disintegrin and metalloproteinase domain 17, a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme), snake venom-like protease, ADAM metallopeptidase domain 17, ADAM18, CD156B, ADAM metallopeptidase domain 18, snake venom-like protease, tumor necrosis factor, alpha, converting enzyme

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  73747889

• Physical Properties:

  Liquid