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ADAM11 Antibody

CAT: 0223-57-458Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-458Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. [provided by RefSeq].
NCBI Gene ID
4185
Swiss Prot
O75078
Accession Number
O75078
Host
Rabbit
Reactivity
Human
Immunogen
This ADAM11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-228 amino acids from the N-terminal region of human ADAM11.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
83 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:500
Symbol
ADAM11
NCBI Official Name
Disintegrin and metalloproteinase domain-containing protein 11
NCBI Organism
Homo sapiens
Background Reference 01
Fu, G.K., et al. Genomics 84 (1) :205-210 (2004)
Background Reference 02
Hillman, R.T., et al. Genome Biol. (2), R8 (2004) :
Background Reference 03
Shea, S.H., et al. Behav. Genet. 31 (2) :231-239 (2001)
Background Reference 04
Sagane, K., et al. Biochem. J. 334 (PT 1), 93-98 (1998) :
Other Product Names
Disintegrin and metalloproteinase domain-containing protein 11, ADAM 11, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein, MDC, ADAM11, MDC
Tested Applications
WB
Physical Properties
Liquid

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