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PARL Antibody

CAT: 0223-39-872Size: 0.1 mgDry Ice: YesHazardous: No
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CAT#:0223-39-872Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PARL is a rhomboid protease which has been shown to be involved in mitochondrial remodeling. PARL has also been shown to have antiapoptotic activity and protects cells from mitochondrial-dependent apoptotic pathway.
NCBI Gene ID
55486
Swiss Prot
Q9H300
Accession Number
NP_001032728
Host
Rabbit
Reactivity
Human, Mouse, Rat, Chicken, Non-Human Primate
Immunogen
Synthetic peptide to the C-terminus.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Apoptosis
Purification
Affinity Purified
Concentration
Batch dependent
Modification
None
Shipping Conditions
Dry Ice
Fragment
IgG
Applications Notes
ELISA, Western (immuno) blotting, Immunostaining (in testing)
Symbol
PARL
NCBI Official Name
Presenilin associated, rhomboid-like
NCBI Organism
Homo sapiens
Background Reference 01
Jeyaraju DV, Xu L, Letellier MC, Bandaru S, Zunino R, Berg EA, McBride HM, Pellegrini L., Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology., Proc Natl Acad Sci U S A. 2006 Dec 5;103 (49) :18562-7.
Background Reference 02
Cipolat S, Rudka T, Hartmann D, Costa V, Serneels L, Craessaerts K, Metzger K, Frezza C, Annaert W, D'Adamio L, Derks C, Dejaegere T, Pellegrini L, D'Hooge R, Scorrano L, De Strooper B., Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling., Cell. 2006 Jul 14;126 (1) :27-9.
Other Product Names
Presenilin associated, rhomboid-like protein , PSARL, PSARL1, RHBDS1, PRO2207, PSENIP2
Tested Applications
ELISA, WB, IHC
Protein ID
143811433
Physical Properties
Liquid

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