Products for Research Use Only
RegisterLogin

PARN Antibody

CAT: 0223-19-242Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-19-242Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly (A) as the substrate, hence, efficiently degrades poly (A) tails of mRNAs. Exonucleolytic degradation of the poly (A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
5073
Swiss Prot
O95453
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PARN (NP_002573.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
MCF7
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 73kDa
Fragment
IgG
Symbol
PARN
Positive Control 2
HepG2
NCBI Official Name
Poly (A) -specific ribonuclease
NCBI Organism
Homo sapiens
Other Product Names
DAN, DKCB6, PFBMFT4, poly (A) -specific ribonuclease PARN, deadenylating nuclease, deadenylation nuclease, polyadenylate-specific ribonuclease
Tested Applications
WB, IHC, IF
Physical Properties
Liquid

Related Products

CatalogName
4761-01mgPARL Antibody
39-872PARL Antibody
31-364PARL Antibody
4761-002mgPARL Antibody
46-994PAR1 Antibody
3171-01mgPARC Antibody
62-792Parg Antibody
4761-01PARL Antibody
3171-01PARC Antibody
3171-002mgPARC Antibody

Alternative Products

CatalogName
20R-1155PARN antibody

Popular Products