BCL11B Antibody

• Background:

  This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.

• NCBI Gene ID:

  64919

• Swiss Prot:

  Q9C0K0

• Accession Number:

  Q9C0K0

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This BCL11B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-334 amino acids from the Central region of human BCL11B.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  96 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:16000

• Symbol:

  BCL11B

• NCBI Official Name:

  B-cell lymphoma/leukemia 11B

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ganguli-Indra, G., et al. Exp. Dermatol. 18 (11) :994-996 (2009)

• Background Reference 02:

  Cherrier, T., et al. Oncogene 28 (38) :3380-3389 (2009)

• Background Reference 03:

  Ganguli-Indra, G., et al. PLoS ONE (4), E5367 (2009) :

• Background Reference 04:

  Cismasiu, V.B., et al. Virology 380 (2) :173-181 (2008)

• Other Product Names:

  B-cell lymphoma/leukemia 11B, BCL-11B, B-cell CLL/lymphoma 11B, COUP-TF-interacting protein 2, Radiation-induced tumor suppressor gene 1 protein, hRit1, BCL11B, CTIP2, RIT1

• Tested Applications:

  WB

• Protein ID:

  44887723

• Physical Properties:

  Liquid