LCE1A Antibody

• Background:

  LCE1A belongs to the late cornified envelope (LCE) gene cluster within the epidermal differentiation complex (EDC) on chromosome 1. The LCE cluster contains multiple conserved genes that encode stratum corneum proteins, and these genes are expressed relatively late during fetal assembly of the skin cornified envelope (Jackson et al., 2005 [PubMed 15854049]) . For further information on the LCE gene cluster, see GENE FAMILY below.

• NCBI Gene ID:

  353131

• Swiss Prot:

  Q5T7P2

• Accession Number:

  Q5T7P2

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This LCE1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-83 amino acids from the C-terminal region of human LCE1A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  11 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  LCE1A

• NCBI Official Name:

  Late cornified envelope protein 1A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Jackson, B., et al. J. Invest. Dermatol. 124 (5) :1062-1070 (2005)

• Background Reference 02:

  Marshall, D., et al. Proc. Natl. Acad. Sci. U.S.A. 98 (23) :13031-13036 (2001)

• Other Product Names:

  Late cornified envelope protein 1A, Late envelope protein 1, LCE1A, LEP1

• Tested Applications:

  WB, IHC-P

• Protein ID:

  74745413

• Physical Properties:

  Liquid