KRT10 Antibody

• Background:

  KRT10 is a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in its gene are associated with epidermolytic hyperkeratosis.

• NCBI Gene ID:

  3858

• Swiss Prot:

  P13645

• Accession Number:

  P13645

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This KRT10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-179 amino acids from the N-terminal region of human KRT10.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  59 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  KRT10

• NCBI Official Name:

  Keratin, type I cytoskeletal 10

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Morais, P., EurDermatol 19 (4), 333-336 (2009)

• Background Reference 02:

  Barcelos, A.C., J. Cutan. Pathol. 36 (6), 647-654 (2009)

• Other Product Names:

  Keratin, type I cytoskeletal 10, Cytokeratin-10, CK-10, Keratin-10, K10, KRT10, KPP

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  269849769

• Physical Properties:

  Liquid