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SYNE3 Antibody

CAT: 0223-55-447Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-447Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system.
NCBI Gene ID
161176
Swiss Prot
Q6ZMZ3
Accession Number
Q6ZMZ3
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This SYNE3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 852-880 amino acids from the C-terminal region of human SYNE3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
112 kDa
Fragment
Rabbit Ig
Symbol
SYNE3
NCBI Official Name
Nesprin-3
NCBI Organism
Homo sapiens
Background Reference 01
Nery, F.C., et al. J. Cell. Sci. 121 (PT 20), 3476-3486 (2008) :
Background Reference 02
Stewart-Hutchinson, P.J., et al. Exp. Cell Res. 314 (8) :1892-1905 (2008)
Background Reference 03
Wilhelmsen, K., et al. J. Cell Biol. 171 (5) :799-810 (2005)
Background Reference 04
Heilig, R., et al. Nature 421 (6923) :601-607 (2003)
Other Product Names
Nesprin-3, Nuclear envelope spectrin repeat protein 3, SYNE3, C14orf49
Tested Applications
WB, IHC-P
Protein ID
134035037
Physical Properties
Liquid

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