ORMDL3 Antibody

• Background:

  Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca (+2) signaling.

• NCBI Gene ID:

  94103

• Swiss Prot:

  Q8N138

• Accession Number:

  Q8N138

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This ORMDL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-81 amino acids from the Central region of human ORMDL3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat, Zebrafish, Xenopus, Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  17 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ORMDL3

• NCBI Official Name:

  ORM1-like protein 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Fransen, K., et al. Hum. Mol. Genet. 19 (17) :3482-3488 (2010) Liu, X., et al. Nat. Genet. 42 (8) :658-660 (2010) Halapi, E., et al. Eur. J. Hum. Genet. 18 (8) :902-908 (2010) Dobbins, S.E., et al. Int. J. Cancer (2010) In pressMcGovern, D.P., et al. Nat. Genet. 42 (4) :332-337 (2010)

• Other Product Names:

  ORM1-like protein 3, ORMDL3

• Tested Applications:

  WB

• Protein ID:

  74728486

• Physical Properties:

  Liquid