Products for Research Use Only
RegisterLogin

ORMDL1 Antibody

CAT: 0223-6313-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-6313-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
ORMDL1 Antibody: The ORMDL (ORM1-like) family of proteins consist of ORMDL1, ORMDL2 and ORMDL3 that may play roles in gamma-secretase complex maturation. Localized to the membrane of the endoplasmic reticulum, ORMDLs are widely expressed and are implicated in the expression of Presenilin (PSI) which is involved in Alzheimer's disease (AD) . Expression of ORMDL1 is down-regulated in PSI mutations, suggesting a possible role as a therapeutic target for AD. ORMDLs have recently been identified as a potential risk factor for childhood asthma.
NCBI Gene ID
94101
Swiss Prot
Q9P0S3
Accession Number
NP_057551
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
ORMDL1 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1220 - SK-N-SH Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (100%), Chicken: (94%)
Buffer
ORMDL1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
ORMDL1 antibody can be stored at 4 ˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
ORMDL1 antibody may cross-react with other ORMDL protein family members.
Symbol
ORMDL1
NCBI Official Name
ORM1-like 1 (S. cerevisiae)
NCBI Organism
Homo sapiens
Background Reference 01
Hjelmqvist L, Tuson M, Marfany G, et al. ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins. Genome Biol. 2002; 3 (6) : RESEARCH0027
Background Reference 02
Araki W, Takahashi-Sasaki N, Chui DH, et al. A family of membrane proteins associated with Presenilin expression and α -secretase function. FASEB J. 2007; 22: 819-827
Background Reference 03
Moffatt MF, Kabesch M, Liang L, et al. Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 2007; 448: 470-473
Background Reference 04
Breslow DK, Collins SR, Bodenmiller B, et al. Orm family proteins mediate sphingolipid homeostasis. Nature. 2010; 463 (7284) :1048-53
Other Product Names
ORMDL1 Antibody: ORM1-like protein 1, Adoplin-1
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
189458852
Physical Properties
Liquid

Related Products

CatalogName
6313PORMDL1 Peptide
55-381ORMDL3 Antibody
55-440ORML2 Antibody
18-180ORM1 Antibody
49-461ORM1 Antibody
XW-7661ORM1 Antibody
62-310ORM1 Antibody
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody

Alternative Products

CatalogName
GTR18078972ORMDL1 Antibody
GTR17891306-01ORMDL1 Antibody (FITC)
CTA2069-01Anti-ORMDL1 Antibody
abx311063-01ORMDL1 Antibody (HRP)
abx311065-01ORMDL1 Antibody (Biotin)
A60126-050ORMDL1 Polyclonal Antibody
NBP1-76577Rabbit Polyclonal ORMDL1 Antibody
A67875-100UGORMDL1 Antibody, Biotin conjugated
A67874-100UGORMDL1 Antibody, FITC conjugated
TA320079ORMDL1 Rabbit Polyclonal Antibody

Popular Products