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HIST1H2BJ Antibody

CAT: 0223-55-372Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-372Size:400 µL
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Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq].
NCBI Gene ID
8970
Swiss Prot
P06899
Accession Number
P06899
Host
Rabbit
Reactivity
Human
Immunogen
This HIST1H2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-86 amino acids from the Central region of human HIST1H2BJ.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Xenopus, Rat, Mouse, Bovine, Monkey, Chicken, Zebrafish
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
14 kDa
Fragment
Rabbit Ig
Symbol
HIST1H2BJ
NCBI Official Name
Histone H2B type 1-J
NCBI Organism
Homo sapiens
Background Reference 01
Shi, J., et al. Nature 460 (7256) :753-757 (2009)
Background Reference 02
Benyamin, B., et al. Am. J. Hum. Genet. 84 (1) :60-65 (2009)
Background Reference 03
Kim, S.C., et al. Mol. Cell 23 (4) :607-618 (2006)
Background Reference 04
Beck, H.C., et al. Mol. Cell Proteomics 5 (7) :1314-1325 (2006)
Other Product Names
Histone H2B type 1-J, Histone H2B1, Histone H2Br, H2B/r, HIST1H2BJ, H2BFR
Tested Applications
WB, IHC-P, Flow
Protein ID
7404367
Physical Properties
Liquid

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