ADORA2A Antibody

• Background:

  ADORA2A is a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G-protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. This protein is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.

• NCBI Gene ID:

  135

• Swiss Prot:

  P29274

• Accession Number:

  P29274

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ADORA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-301 amino acids from the Central region of human ADORA2A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Obesity, Neuroscience, Signal Transduction, Growth Factors

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  45 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ADORA2A

• NCBI Official Name:

  Adenosine receptor A2a

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Buira, S.P., et al. J. Neurochem. 115 (1) :283-295 (2010)

• Background Reference 02:

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 03:

  Rogers, P.J., et al. Neuropsychopharmacology 35 (9) :1973-1983 (2010)

• Background Reference 04:

  Tebano, M.T., et al. ScientificWorldJournal 10, 1768-1782 (2010) :

• Other Product Names:

  Adenosine receptor A2a, ADORA2A, ADORA2

• Tested Applications:

  WB, IF

• Protein ID:

  543740

• Physical Properties:

  Liquid