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SAR1B Antibody

CAT: 0223-55-163Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-163Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD) . Two transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
51128
Swiss Prot
Q9Y6B6
Accession Number
Q9Y6B6
Host
Rabbit
Reactivity
Human
Immunogen
This SAR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-116 amino acids from the Central region of human SAR1B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
22 kDa
Fragment
Rabbit Ig
Symbol
SAR1B
NCBI Official Name
GTP-binding protein SAR1b
NCBI Organism
Homo sapiens
Background Reference 01
Cefalu, A.B., et al. Metab. Clin. Exp. 59 (4) :463-467 (2010)
Background Reference 02
Silvain, M., et al. Clin. Genet. 74 (6) :546-552 (2008)
Background Reference 03
Charcosset, M., et al. Mol. Genet. Metab. 93 (1) :74-84 (2008)
Background Reference 04
Jardim, D.L., et al. J. Biochem. Mol. Biol. 38 (3) :328-333 (2005)
Other Product Names
GTP-binding protein SAR1b, GTP-binding protein B, GTBPB, SAR1B, SARA2, SARB
Tested Applications
WB, IHC-P, Flow
Protein ID
14285769
Physical Properties
Liquid

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