Interferon alpha Antibody [2.52]

• Background:

  This mAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1) . Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

• NCBI Gene ID:

  3439

• Swiss Prot:

  P01562

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Purified recombinant human IFNA1 was used as the immunogen for the Interferon alpha antibody.

• Clonality:

  Monoclonal

• Clone:

  2.52

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Cancer

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG1, kappa

• Symbol:

  IFNA1

• NCBI Official Name:

  Interferon alpha 1

• NCBI Organism:

  Homo sapiens

• Tested Applications:

  WB, ELISA

• Physical Properties:

  Liquid