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Interferon alpha 2 Antibody [N39]

CAT: 0223-33-405Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0223-33-405Size:100 µg
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Background
Recognizes a protein of 16-27kDa, identified as human interferon-II) (IFN- (II) . Its epitope maps between aa112-148 of IFN-II) (total aa172) . This mAb is specific for IFN- (II) and does not cross-react with IFN- (I) . The site recognized by this mAb is called "site I" and is responsible for the antiviral and anti-proliferative activities of IFN- (II) . Epitopes of N27 and N39 mAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN- (II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.
NCBI Gene ID
3440
Swiss Prot
P01563
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant human IFNA2 was used as the immunogen for the Interferon alpha 2 antibody.
Clonality
Monoclonal
Clone
N39
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Chemokines & Cytokines
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG, kappa
Symbol
IFNA2
NCBI Official Name
Interferon, alpha 2
NCBI Organism
Homo sapiens
Other Product Names
Interferon alpha-2, Interferon alpha-A, IFN-alpha-2, IFNA, INFA2, IFNA2B, IFN-alphaA
Tested Applications
WB, ELISA
Physical Properties
Liquid

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