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Interferon alpha 1 (2.52), 1mg/mL

CAT: 0037-BNUM0998-50Size: 1x 50 µLDry Ice: NoHazardous: No
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Description
This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1) . Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
CAS Number
9007-83-4
Synonyms
IFN alpha; IFN alpha 1/13; IFN alpha 1b; Interferon alpha 13 (IFNA13) ; Interferon alpha leukocyte (IFL) ; Interferon alpha-1/13 (IFN-alpha-1/13) ; Interferon alpha-D (IFN alphaD) ; Interferon alpha1 (IFNA1) ; LeIF D
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IFNA1
Gene ID
3439
NCBI Gene ID
37026 & 533471
UniProt
P01562
Swiss Prot
P01562
Host
Mouse
Species Reactivity
Human
Reactivity
Interferon Alpha-1
Immunogen
Purified recombinant human IFN-alpha1
Target Antigen
Interferon Alpha-1
Clonality
Monoclonal
Clone
2.52
Type
Primary
Source
Animal
Origin
Animal
Field of Research
Cytokines, Immunology, Inflammation
Positive Control
Stimulated human peripheral blood mononuclear cells
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
16-27 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

UniProtKB · P0DY56

Interferon alpha-1

IFNA1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P0DY56
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IFNA1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IFN-alpha-1
EC number
—
Processing
Precursor
Secondary accessions
D4Q9M8, P01562, Q14605, Q2M1L8, Q52LB8, Q5VYQ2, Q7M4Q1, Q8WZ68, Q9UMJ3
Protein keywords

Technical term

3D-structureDirect protein sequencingReference proteome

Biological process

Antiviral defense

Molecular function

Cytokine

PTM

Disulfide bond

Cellular component

Secreted

Domain

Signal
Product Datasheet
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