RUNX3 Antibody [RNX864]

• Background:

  The Runt family of transcription factors is involved in both normal cell development and carcinogenesis. Runt-related transcription factor 3 has been shown to be a tumor suppressor. Hypermethylation and mislocalization of the protein to the cytoplasm leads to low levels of RUNX3 and increased proliferation of breast and gastric tumor cells.

• NCBI Gene ID:

  864

• Swiss Prot:

  Q13761

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A RUNX3 recombinant protein fragment was used as the immunogen for this antibody.

• Clonality:

  Monoclonal

• Clone:

  RNX864

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Protein G Affinity Chromatography

• Concentration:

  0.5 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at -20˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG1, kappa

• Symbol:

  RUNX3

• NCBI Official Name:

  Runt-related transcription factor 3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Runt-related transcription factor 3, Acute myeloid leukemia 2 protein, Core-binding factor subunit alpha-3, CBF-alpha-3, Oncogene AML-2, Polyomavirus enhancer-binding protein 2 alpha C subunit, PEA2-alpha C, PEBP2-alpha C, SL3-3 enhancer factor 1 alpha C subunit, SL3/AKV core-binding factor alpha C subunit, RUNX3, AML2, CBFA3, PEBP2A3

• Tested Applications:

  WB

• Physical Properties:

  Liquid