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L2HGDH Antibody

CAT: 0223-55-109Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-109Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.
NCBI Gene ID
79944
Swiss Prot
Q9H9P8
Accession Number
Q9H9P8
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This L2HGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-159 amino acids from the Central region of human L2HGDH.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
50 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
L2HGDH
NCBI Official Name
L-2-hydroxyglutarate dehydrogenase, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Short, A.D., et al. Vet. Rec. 167 (12) :455-457 (2010)
Background Reference 02
Steenweg, M.E., et al. Hum. Mutat. 31 (4) :380-390 (2010)
Background Reference 03
Kranendijk, M., et al. Hum. Mutat. 31 (3) :279-283 (2010)
Background Reference 04
Vilarinho, L., et al. J. Hum. Genet. 55 (1) :55-58 (2010)
Other Product Names
L-2-hydroxyglutarate dehydrogenase, mitochondrial, Duranin, L2HGDH, C14orf160
Tested Applications
WB
Protein ID
317373422
Physical Properties
Liquid

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