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BCAT1 Antibody

CAT: 0223-55-059Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-059Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.
NCBI Gene ID
586
Swiss Prot
P54687
Accession Number
P54687
Host
Rabbit
Reactivity
Human
Immunogen
This BCAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-107 amino acids from the Central region of human BCAT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
43 kDa
Fragment
Rabbit Ig
Symbol
BCAT1
NCBI Official Name
Branched-chain-amino-acid aminotransferase, cytosolic
NCBI Organism
Homo sapiens
Background Reference 01
Eijgelsheim, M., et al. Hum. Mol. Genet. 19 (19) :3885-3894 (2010)
Background Reference 02
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 03
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 04
Barber, M.J., et al. PLoS ONE (3), E9763 (2010) :
Other Product Names
Branched-chain-amino-acid aminotransferase, cytosolic, BCAT (c), Protein ECA39, BCAT1, BCT1, ECA39
Tested Applications
WB, IHC-P
Protein ID
215274162
Physical Properties
Liquid

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