PDCD4 Antibody

• Background:

  PDCD4 is a protein localized to the nucleus in proliferating cells. Expression of its gene is modulated by cytokines in natural killer and T cells. PDCD4 is thought to play a role in apoptosis but the specific role has not yet been determined.This gene encodes a protein localized to the nucleus in proliferating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is thought to play a role in apoptosis but the specific role has not yet been determined. Two transcripts encoding different isoforms have been identified.

• NCBI Gene ID:

  27250

• Swiss Prot:

  Q53EL6

• Accession Number:

  NP_663314

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PDCD4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Apoptosis

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PDCD4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  50 kDa

• Applications Notes:

  PDCD4 antibody can be used for detection of PDCD4 by ELISA at 1:12500. PDCD4 antibody can be used for detection of PDCD4 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  PDCD4

• NCBI Official Name:

  Programmed cell death 4 (neoplastic transformation inhibitor)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yang, H.S., (2006) Mol. Cell. Biol. 26 (4), 1297-1306.

• Other Product Names:

  PDCD4, H731, MGC33046, MGC33047

• Tested Applications:

  ELISA, WB

• Protein ID:

  21735598

• Physical Properties:

  Liquid