EIF2AK2 Antibody

• Background:

  EIF2AK2 might play a role in ER stress-induced apoptosis and in Alzheimer's disease. Alzheimer cases show prominent EIF2AK2 activation in association with neuritic plaques and pyramidal neurons in the hippocampus and neocortex.

• NCBI Gene ID:

  5610

• Swiss Prot:

  P19525

• Accession Number:

  NP_002750

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EIF2AK2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Cancer, Signal Transduction, Immunology

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1201 - HeLa Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store EIF2AK2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  62 kDa

• Applications Notes:

  EIF2AK2 antibody can be used for detection of EIF2AK2 by ELISA at 1:1562500. EIF2AK2 antibody can be used for detection of EIF2AK2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  EIF2AK2

• NCBI Official Name:

  Eukaryotic translation initiation factor 2-alpha kinase 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Nallagatla, S.R. (2008) RNA 14 (6), 1201-1213.

• Other Product Names:

  EIF2AK2, EIF2AK1, MGC126524, PKR, PRKR

• Tested Applications:

  ELISA, WB

• Protein ID:

  4506103

• Physical Properties:

  Liquid