APPBP2 Antibody

• Background:

  APPBP2 interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. APPBP2 has been found to be highly expressed in breast cancer.The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene.

• NCBI Gene ID:

  10513

• Swiss Prot:

  Q92624

• Accession Number:

  NP_006371

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human APPBP2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. XBL-10123 - Fetal Brain Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store APPBP2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  67 kDa

• Applications Notes:

  APPBP2 antibody can be used for detection of APPBP2 by ELISA at 1:312500. APPBP2 antibody can be used for detection of APPBP2 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  APPBP2

• NCBI Official Name:

  Amyloid beta precursor protein (cytoplasmic tail) binding protein 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Benboudjema, L., (2003) J. Virol. 77 (17), 9192-9203.

• Other Product Names:

  APPBP2, HS.84084, KIAA0228, PAT1, APP-BP2

• Tested Applications:

  ELISA, WB

• Protein ID:

  18104962

• Physical Properties:

  Liquid