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APPL2 Antibody

CAT: 0223-59-215Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-215Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Required for the regulation of cell proliferation in response to extracellular signals mediated by an early endosomal compartment. Links Rab5 to nuclear signal transduction.
NCBI Gene ID
55198
Swiss Prot
Q8NEU8
Accession Number
Q8NEU8
Host
Rabbit
Reactivity
Human
Immunogen
This APPL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-152 amino acids from the N-terminal region of human APPL2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
74 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
APPL2
NCBI Official Name
DCC-interacting protein 13-beta
NCBI Organism
Homo sapiens
Background Reference 01
Chial, H.J., et al. PLoS ONE (8), E12471 (2010) :
Background Reference 02
Rashid, S., et al. J. Biol. Chem. 284 (27) :18115-18128 (2009)
Background Reference 03
Chial, H.J., et al. Traffic 9 (2) :215-229 (2008)
Background Reference 04
Nechamen, C.A., et al. Mol. Cell. Endocrinol. 260-262, 93-99 (2007) :
Other Product Names
DCC-interacting protein 13-beta, Dip13-beta, Adapter protein containing PH domain, PTB domain and leucine zipper motif 2, APPL2, DIP13B
Tested Applications
WB
Protein ID
160419148
Physical Properties
Liquid

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