MBNL2 Antibody

CAT: 0223-30-736Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-30-736Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM) .
NCBI Gene ID
10150
Swiss Prot
O95205
Accession Number
NP_005748
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MBNL2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MBNL2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
28 kDa
Applications Notes
MBNL2 antibody can be used for detection of MBNL2 by ELISA at 1:1562500. MBNL2 antibody can be used for detection of MBNL2 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
MBNL2
NCBI Official Name
Muscleblind-like splicing regulator 2
NCBI Organism
Homo sapiens
Other Product Names
MBNL2, DKFZp781H1296, MBLL, MBLL39, MGC120625, MGC120626, MGC120628, PRO2032, RP11-128N14.1
Tested Applications
ELISA, WB
Protein ID
5031903
Physical Properties
Liquid

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