ALG2 Antibody

• Background:

  ALG2 is a member of the glycosyltransferase 1 family. It acts as an alpha 1,3 mannosyltransferase, mannosylating Man (2) GlcNAc (2) -dolichol diphosphate and Man (1) GlcNAc (2) -dolichol diphosphate to form Man (3) GlcNAc (2) -dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii) .This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man (2) GlcNAc (2) -dolichol diphosphate and Man (1) GlcNAc (2) -dolichol diphosphate to form Man (3) GlcNAc (2) -dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii) . Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

• NCBI Gene ID:

  85365

• Swiss Prot:

  Q9H553

• Accession Number:

  NP_149078

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ALG2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ALG2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  47 kDa

• Applications Notes:

  ALG2 antibody can be used for detection of ALG2 by ELISA at 1:312500. ALG2 antibody can be used for detection of ALG2 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  ALG2

• NCBI Official Name:

  ALG2, alpha-1,3/1,6-mannosyltransferase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Draeby, I., (2007) Arch. Biochem. Biophys. 467 (1), 87-94.

• Other Product Names:

  ALG2, CDGIi, FLJ14511, hALPG2, NET38

• Tested Applications:

  ELISA, WB

• Protein ID:

  14861836

• Physical Properties:

  Liquid