CDT1 Antibody

• Background:

  CDT1 cooperates with CDC6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the pre-replication complex necessary to initiate DNA replication. It binds DNA in a sequence-, strand-, and conformation-independent manner and is a potential oncogene.

• NCBI Gene ID:

  81620

• Swiss Prot:

  Q9H211

• Accession Number:

  NP_112190

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDT1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Cancer

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store CDT1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  60 kDa

• Applications Notes:

  CDT1 antibody can be used for detection of CDT1 by ELISA at 1:62500. CDT1 antibody can be used for detection of CDT1 by western blot at 1.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  CDT1

• NCBI Official Name:

  Chromatin licensing and DNA replication factor 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hu, J. (2006) J. Biol. Chem. 281 (7), 3753-3756.

• Other Product Names:

  CDT1, DUP, RIS2

• Tested Applications:

  ELISA, WB

• Protein ID:

  188497689

• Physical Properties:

  Liquid