ALPPL2 Antibody

• Background:

  There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific) . The exact physiological function of the alkaline phosphatases is not known. ALPPL2 is a membrane bound glycosylated enzyme, localized to testis, thymus and certain germ cell tumors, that is closely related to both the placental and intestinal forms of alkaline phosphatase.There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific) . The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The exact physiological function of the alkaline phosphatases is not known. The product of this gene is a membrane bound glycosylated enzyme, localized to testis, thymus and certain germ cell tumors, that is closely related to both the placental and intestinal forms of alkaline phosphatase.

• NCBI Gene ID:

  251

• Swiss Prot:

  P10696

• Accession Number:

  NP_112603

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ALPPL2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ALPPL2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  59 kDa, 58 kDa

• Applications Notes:

  ALPPL2 antibody can be used for detection of ALPPL2 by ELISA at 1:312500. ALPPL2 antibody can be used for detection of ALPPL2 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  ALPPL2

• NCBI Official Name:

  Alkaline phosphatase, placental-like 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Nakano, T., (2006) Biochem. Biophys. Res. Commun. 341 (1), 33-38.

• Other Product Names:

  ALPPL2, ALPG, ALPPL, GCAP

• Tested Applications:

  ELISA, WB

• Protein ID:

  157266296

• Physical Properties:

  Liquid