ALPP Antibody

• Background:

  The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells.

• NCBI Gene ID:

  250

• Swiss Prot:

  P05187

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 260-460 of human ALPP (NP_001623.3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Stem Cell

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 70kDa

• Fragment:

  IgG

• Symbol:

  ALPP

• NCBI Official Name:

  Alkaline phosphatase, placental

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ALPP, ALP, PLAP, PALP, PLAP-1

• Tested Applications:

  WB, IP

• Physical Properties:

  Liquid