APCS Antibody

CAT: 0223-29-679Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-29-679Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
APCS is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. This gene has multiple polyadenylation sites.
NCBI Gene ID
325
Swiss Prot
P02743
Accession Number
NP_001630
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human APCS.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction, Immunology
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store APCS antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
25 kDa
Applications Notes
APCS antibody can be used for detection of APCS by ELISA at 1:62500. APCS antibody can be used for detection of APCS by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
APCS
NCBI Official Name
Amyloid P component, serum
NCBI Organism
Homo sapiens
Background Reference 01
Veerhuis, R., Neurobiol. Dis. 19 (1-2), 273-282 (2005) .
Other Product Names
APCS, MGC88159, PTX2, SAP, HEL-S-92n
Tested Applications
ELISA, WB, IHC
Protein ID
4502133
Physical Properties
Liquid

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