APC2 Antibody

• Background:

  APC2 belongs to the adenomatous polyposis coli (APC) family. It contains 6 ARM repeats. APC2 promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. It may function in Wnt signaling.

• NCBI Gene ID:

  10297

• Swiss Prot:

  Q9UJX6

• Accession Number:

  NP_005874

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human APC2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Cancer, Signal Transduction, Apoptosis

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1309 - Human Placenta Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store APC2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  244 kDa

• Applications Notes:

  APC2 antibody can be used for detection of APC2 by ELISA at 1:62500. APC2 antibody can be used for detection of APC2 by western blot at 0.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  APC2

• NCBI Official Name:

  Adenomatosis polyposis coli 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Attard, T.M., (2008) Dis. Colon Rectum 51 (2), 207-212.

• Other Product Names:

  APC2, APCL

• Tested Applications:

  ELISA, WB

• Protein ID:

  5031587

• Physical Properties:

  Liquid