GNB1L Antibody

GNB1L is a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. Therefore, this gene may contribute to the etiology of those disorders.This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome. Therefore, this gene may contribute to the etiology of those disorders.

54584

Q9BYB4

NP_443730

Human, Mouse, Rat

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GNB1L.

Unconjugated

Primary Antibodies

Signal Transduction, Immunology

Antibody is purified by protein A chromatography method.

Cat. No. 1205 - Jurkat Cell Lysate

Batch dependent

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

None

Blue Ice

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GNB1L antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

36 kDa

GNB1L antibody can be used for detection of GNB1L by ELISA at 1:12500. GNB1L antibody can be used for detection of GNB1L by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

GNB1L

Guanine nucleotide binding protein (G protein), beta polypeptide 1-like

Homo sapiens

Collins, J.E., Genome Biol. 5 (10), R84 (2004) .

GNB1L, GY2, FKSG1, WDR14, WDVCF, DGCRK3

ELISA, WB, IHC

17402902