SYNCRIP Antibody

• Background :

  Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. SYNCRIP may be involved in translationally coupled mRNA turnover. It implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. It interacts in vitro preferentially with poly (A) and poly (U) RNA sequences.

• NCBI Gene ID :

  10492

• Swiss Prot :

  O60506

• Accession Number :

  NP_006363

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat, Dog

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SYNCRIP.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Antibody is purified by protein A chromatography method.

• Positive Control :

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SYNCRIP antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  69 kDa

• Applications Notes :

  SYNCRIP antibody can be used for detection of SYNCRIP by ELISA at 1:312500. SYNCRIP antibody can be used for detection of SYNCRIP by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  SYNCRIP

• NCBI Official Name :

  Synaptotagmin binding, cytoplasmic RNA interacting protein

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Bannai, H., (2004) J. Biol. Chem. 279 (51), 53427-53434.

• Other Product Names :

  SYNCRIP, PP68, NSAP1, GRYRBP, HNRNPQ, HNRPQ1, GRY-RBP, hnRNP-Q

• Tested Applications :

  ELISA, WB

• Protein ID :

  228008291

• Physical Properties :

  Liquid