SYNCRIP Antibody

• Background:

  Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. SYNCRIP may be involved in translationally coupled mRNA turnover. It implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. It interacts in vitro preferentially with poly (A) and poly (U) RNA sequences.

• NCBI Gene ID:

  10492

• Swiss Prot:

  O60506

• Accession Number:

  NP_006363

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SYNCRIP.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SYNCRIP antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  69 kDa

• Applications Notes:

  SYNCRIP antibody can be used for detection of SYNCRIP by ELISA at 1:312500. SYNCRIP antibody can be used for detection of SYNCRIP by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  SYNCRIP

• NCBI Official Name:

  Synaptotagmin binding, cytoplasmic RNA interacting protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bannai, H., (2004) J. Biol. Chem. 279 (51), 53427-53434.

• Other Product Names:

  SYNCRIP, PP68, NSAP1, GRYRBP, HNRNPQ, HNRPQ1, GRY-RBP, hnRNP-Q

• Tested Applications:

  ELISA, WB

• Protein ID:

  228008291

• Physical Properties:

  Liquid