SYNCI Antibody

• Background:

  This gene encodes a member of the intermediate filament family which contains an N-terminal head domain, followed by a central coiled-coil region and a short C-terminal tail. The protein is highly expressed in skeletal and cardiac muscle. The protein links the dystrophin associated protein complex (DAPC) to desmin filaments in muscle and may have a structural role in striated muscle. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  81493

• Swiss Prot:

  Q9H7C4

• Accession Number:

  Q9H7C4

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SYNCI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 129-158 amino acids from the N-terminal region of human SYNCI.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  55 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SYNC

• NCBI Official Name:

  Syncoilin

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wakayama, Y., et al. Int. J. Neurosci. 120 (2) :144-149 (2010)

• Background Reference 02:

  Jordanova, A., et al. Nat. Genet. 38 (2) :197-202 (2006)

• Background Reference 03:

  Brown, S.C., et al. Muscle Nerve 32 (6) :715-725 (2005)

• Background Reference 04:

  Poon, E., et al. J. Biol. Chem. 277 (5) :3433-3439 (2002)

• Other Product Names:

  Syncoilin, Syncoilin intermediate filament 1, Syncoilin-1, SYNC, SYNC1

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  300669677

• Physical Properties:

  Liquid