EZH2 Antibody

• Background:

  EZH2 is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems.

• NCBI Gene ID:

  2146

• Swiss Prot:

  Q15910

• Accession Number:

  EAW80068

• Host:

  Rabbit

• Reactivity:

  Human, Dog, Zebrafish

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human EZH2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cancer

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1211 - HepG2 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store EZH2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  37 kDa, 86 kDa, 81 kDa

• Applications Notes:

  EZH2 antibody can be used for detection of EZH2 by ELISA at 1:1562500. EZH2 antibody can be used for detection of EZH2 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  EZH2

• NCBI Official Name:

  Enhancer of zeste homolog 2 (Drosophila)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Mural, R.J., (2005) Direct Submission.

• Other Product Names:

  EZH2, WVS, ENX1, EZH1, KMT6, WVS2, ENX-1, EZH2b, KMT6A

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  119600474

• Physical Properties:

  Liquid