TRIP13 Antibody

CAT: 0223-28-870Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-28-870Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The thyroid hormone (T3) receptors (TRs) are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. TRIP13 specifically interacts with the ligand binding domain of the TRs. It is a member of Trips (TR-interacting proteins) family. Nearly all of the Trips also show similar ligand-dependent interaction with the retinoid X receptor (RXR), but none interact with the glucocorticoid receptor under any conditions. Trips predict specific functional roles: one is an apparent human homolog of a yeast transcriptional coactivator, one is a new member of a class of nonhistone chromosomal proteins, and one contains a conserved domain associated with ubiquitination of specific target proteins.
NCBI Gene ID
9319
Swiss Prot
Q15645
Accession Number
NP_004228
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRIP13.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer, Signal Transduction
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TRIP13 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
49 kDa
Applications Notes
TRIP13 antibody can be used for detection of TRIP13 by ELISA at 1:312500. TRIP13 antibody can be used for detection of TRIP13 by western blot at 5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
TRIP13
NCBI Official Name
Thyroid hormone receptor interactor 13
NCBI Organism
Homo sapiens
Background Reference 01
Rual, J.F., et al., (2005) Nature 437 (7062), 1173-1178.
Other Product Names
TRIP13, 16E1BP
Tested Applications
ELISA, WB
Protein ID
11321607
Physical Properties
Liquid

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