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RUNX1 Antibody

CAT: 0223-28-784Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-28-784Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. RUNX1 is the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with severaltypes of leukemia.
NCBI Gene ID
861
Swiss Prot
Q01196
Accession Number
AAC05247
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RUNX1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RUNX1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
12 kDa
Applications Notes
RUNX1 antibody can be used for detection of RUNX1 by ELISA at 1:12500. RUNX1 antibody can be used for detection of RUNX1 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
RUNX1
NCBI Official Name
Runt-related transcription factor 1
NCBI Organism
Homo sapiens
Background Reference 01
Ghozi, M.C., et al., (1996) Proc. Natl. Acad. Sci. U.S.A. 93 (5), 1935-1940.
Other Product Names
RUNX1, AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, AML1-EVI-1
Tested Applications
ELISA, WB
Protein ID
2944214
Physical Properties
Liquid

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