BACH1 Antibody

• Background:

  BACH1 is a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip) . The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. Some exons of this gene overlap with some exons from the C21orf41 gene, which is transcribed in an opposite orientation to this gene but does not seem to encode a protein.

• NCBI Gene ID:

  571

• Swiss Prot:

  O14867

• Accession Number:

  NP_001177

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BACH1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store BACH1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  82 kDa, 82 kDa

• Applications Notes:

  BACH1 antibody can be used for detection of BACH1 by ELISA at 1:1562500. BACH1 antibody can be used for detection of BACH1 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  BACH1

• NCBI Official Name:

  BTB and CNC homology 1, basic leucine zipper transcription factor 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Litman, R., et al., (2005) Cancer Cell 8 (3), 255-265.

• Other Product Names:

  BACH1, BACH-1, AP000240.4

• Tested Applications:

  ELISA, WB

• Protein ID:

  4502353

• Physical Properties:

  Liquid