ISL2 Antibody

• Background:

  Isl2 specifies RGC laterality by repressing an ipsilateral pathfinding program unique to VTC RGCs and involving Zic2 and EphB1. This genetic hierarchy controls binocular vision.

• NCBI Gene ID:

  104360

• Swiss Prot:

  Q9CXV0

• Accession Number:

  NP_081673

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ISL2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  SP2/0 Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ISL2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  39 kDa

• Applications Notes:

  ISL2 antibody can be used for detection of ISL2 by ELISA at 1:312500. ISL2 antibody can be used for detection of ISL2 by western blot at 5.0 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  ISL2

• NCBI Official Name:

  Insulin related protein 2 (islet 2)

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Svard, J., et al., (2006) Dev. Cell 10 (2), 187-197.

• Other Product Names:

  ISL2, 3110001N10Rik

• Tested Applications:

  ELISA, WB

• Protein ID:

  154146254

• Physical Properties:

  Liquid