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GJB1 Antibody

CAT: 0223-28-526Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-28-526Size:100 µL
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Background
This gene encodes for a Connexin 32 protein. A large Charcot-Marie-Tooth disease family has been identified with a novel mutation in the Cx32 P2 promoter region at position -526bp. Cx32 mutants that are associated with a CNS phenotype may have toxic effects in oligodendrocytes.
NCBI Gene ID
2705
Swiss Prot
P08034
Accession Number
NP_000157
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GJB1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer, Signal Transduction, Neuroscience
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store GJB1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
31 kDa
Applications Notes
GJB1 antibody can be used for detection of GJB1 by ELISA at 1:312500. GJB1 antibody can be used for detection of GJB1 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
GJB1
NCBI Official Name
Gap junction protein, beta 1, 32kDa
NCBI Organism
Homo sapiens
Background Reference 01
Dagli, M.L., et al., (2004) Carcinogenesis 25 (4), 483-492.
Other Product Names
GJB1, CMTX, CX32, CMTX1
Tested Applications
ELISA, WB, IHC
Protein ID
4504005
Physical Properties
Liquid

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